期刊
BEHAVIORAL NEUROSCIENCE
卷 119, 期 1, 页码 202-212出版社
AMER PSYCHOLOGICAL ASSOC
DOI: 10.1037/0735-7044.119.1.202
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资金
- NIMH NIH HHS [R37 MH053667, R01 MH053667, MH53667] Funding Source: Medline
In Pavlovian appetitive conditioning, rats often acquire 2 classes of conditioned responses: those whose form is determined by the reinforcer, and those whose form is determined by characteristics of the conditioned stimulus (CS). Consistent with the results of previous lesion studies, reversible inactivation of amygdala central nucleus function during pairings of an auditory CS with food prevented the acquisition of conditioned orienting responses specific to auditory CSs, whereas food-related conditioned behaviors were acquired normally. Neither inactivation nor posttraining neurotoxic lesions of the central nucleus affected the expression of previously acquired conditioned orienting. Thus, although the central nucleus is critical to the acquisition of information required for conditioned orienting to auditory cues, it is not needed for maintaining this information for later use.
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