期刊
INFLAMMATORY BOWEL DISEASES
卷 11, 期 2, 页码 185-196出版社
OXFORD UNIV PRESS INC
DOI: 10.1097/00054725-200502000-00013
关键词
clinical trails; Crohn's disease; pediatrics
The necessity to include children and adolescents in clinical trials is increasingly recognized. Two recent workshops provided the impetus for pediatric gastroenterologists to develop evidence-based recommendations concerning end points and outcome assessment in cases of pediatric Crohn's disease. The overall goal was to facilitate clinical trial design by standardizing the methodology. This article critically reviews the available assessment tools and provides consensus recommendations for the evaluation of linear growth, disease activity, and health-related quality of life in clinical trials in pediatric Crohn's disease.
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