期刊
INTERNATIONAL JOURNAL OF STD & AIDS
卷 16, 期 2, 页码 95-101出版社
SAGE PUBLICATIONS LTD
DOI: 10.1258/0956462053057576
关键词
HIV; TB; co-infection; review; drug interactions
资金
- Wellcome Trust [063643] Funding Source: Medline
Co-infection with HIV and Mycobacterium tuberculosis is common, particularly in the developing world. Tuberculosis (TB) is the commonest co-infection in HIV-positive individuals, who are at increased risk of both reactivation of latent infection and acquisition of new infection. As the degree of immunosuppression increases, the risks of developing TB disease also increase. The pathophysiology, clinical picture, differential diagnosis and diagnostic tests are discussed, together with the interactions between antiretroviral therapy and anti-tuberculous chemotherapy. Indications for chemoprophylaxis and vaccination against TB are reviewed.
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