期刊
NATURE STRUCTURAL & MOLECULAR BIOLOGY
卷 12, 期 2, 页码 110-112出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb0205-110
关键词
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The tails of the four core histones are exposed on the nucleosome surface, where they are subject to a variety of enzyme-catalyzed, post-translational modifications. Modifications, singly or in combination, provide a source of information that can be used for signal transduction during ongoing processes, such as transcription, or as heritable epigenetic marks. A nomenclature is presented that allows patterns of histone modification to be clearly and unambiguously specified and that should facilitate discussion of their functional roles.
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