The relationship between the systemic inflammatory response and survival in patients with transitional cell carcinoma of the urinary bladder

The relationship between tumour stage, grade, elevated C-reactive protein concentration (<10/ >10 mg l(-1)), adjuvant therapy and survival was examined in patients with biopsy proven bladder cancer (n = 105). On multivariate analysis stage (HR 3.37, 95% CI 1.37 - 8.29, P = 0.008), grade (HR 2.01, 95% CI 1.14 - 3.57, P = 0.017) and preoperative C-reactive protein (HR 3.31, 95% CI 1.09-10.09, P = 0.035) were independently associated with cancer-specific survival.