期刊
SCHIZOPHRENIA RESEARCH
卷 73, 期 2-3, 页码 173-184出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.schres.2004.05.021
关键词
prodrome; psychosis; ethics; treatment; risk; schizophrenia
类别
资金
- NIMH NIH HHS [R01 MH59114, MH01699 K24, K24 MH001699, K24 MH001699-01A2, R01 MH059114, K23 MH066279, R01 MH059114-01A1] Funding Source: Medline
Given the morbidity and difficulty of treating psychotic disorders, including schizophrenia, there has been a move toward identifying and treating adolescents and young adults who appear to be clinically at risk or prodromal, to psychosis. The field now has greater specificity in identification, with rates of 40-50% conversion to frank psychosis within 1-2 years. There is further evidence that medications and other treatments may have some efficacy for prodromal patients, though with variable side effects. However, controversy remains about some of the inherent risks in prodromal research, such as medication exposure and stigma among false-positives. In this paper, we add to this discussion through an analysis of ethics in prodromal research from the more established field of predictive genetic testing. Issues are raised about the effects of information on patients, families, and institutions, as well as future insurability, the limits of confidentiality (as it relies on discretion of patients and families), the autonomy of minors with psychiatric symptoms, and even the risks for the true-positive patient. (C) 2004 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据