期刊
JOURNAL OF CLINICAL EPIDEMIOLOGY
卷 58, 期 3, 页码 246-251出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jclinepi.2004.08.012
关键词
cluster randomization; cluster sampling; intraclass correlation coefficient; Kappa; binary data; prevalence
Background and Objective: To describe the association between values for a proportion and the intraclass correlation coefficient (ICC). Methods: Analysis of data obtained from the General Practice Research Database (GPRD) for variation between United Kingdom general practices and results from a Health Technology Assessment (HTA) review for a range of outcomes in community and health services settings. Results: There were 188 ICCs from the GPRD, the median prevalence was 13.1% (interquartile range IQR 3.5 to 28.4%) and median ICC 0.051 (IQR 0.011 to 0.094). There were 136 ICCs from the HTA review, with median prevalence 6.5% (IQR 0.4 to 20.7%) and median ICC 0.006 (IQR 0.0003 to 0.036). There was a linear association of log ICC with log prevalence in both datasets (GPRD, regression coefficient 0.61, 95% confidence interval 0.53 to 0.69, P < 0.001; HTA, 0.91, 0.81 to 1.01, P < 0.001). When the prevalence was 1% the predicted ICC was 0.008 from the GPRD or 0.002 from the HTA, but when the prevalence was 40% the predicted ICC was 0.075 (GPRD) or 0.046 (HTA). Conclusion: The prevalence of an outcome may be used to make an informed assumption about the magnitude of the intraclass correlation coefficient. (C) 2005 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据