4.6 Article

Does antenatal identification of small-for-gestational age fetuses significantly improve their outcome?

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ULTRASOUND IN OBSTETRICS & GYNECOLOGY
卷 25, 期 3, 页码 258-264

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WILEY
DOI: 10.1002/uog.1806

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antenatal identification; Doppler surveillance; intrauterine growth restriction; outcome complication; prenatal diagnosis

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Objectives Most obstetric clinics have a program for the identification of small-for-gestational age (SGA) fetuses because of the increased risk of fetal complications that they present. We have a structured model for the identification and follow-up of SGA pregnancies. We aimed to determine whether the recognition of SGA antepartum improves fetal outcome. Methods All pregnancies at Malmo University Hospital from 1990 to 1998 (n = 26 968) were reviewed. SGA fetuses identified prior to delivery (n 681) were compared with those not identified (n 573). Also, all pregnancies with SGA fetuses were compared with those appropriate-for-gestational age (AGA) (n = 24 585). The risk of serious fetal complications (hypoxic encephalopathy grade 2 or 3, intracranial hemorrhage, Apgar score < 4 at 5 min, neonatal convulsions, umbilical pH < 7.0, cerebral palsy, mental retardation, stillbirth, intrapartum or infant death) was assessed with cross-tabulation and logistic regression analysis, adjusted for gestational age and degree of SGA. Results When compared with SGA fetuses identified before delivery (54%), SGA fetuses not identified before delivery were characterized by a four-fold increased risk of adverse fetal outcome (odds ratio, 4.1; 95% CI, 2.5-6.8). Similarly, compared with AGA fetuses, SGA fetuses were associated with a four-fold increased risk of serious fetal complications. Conclusions A structured antenatal surveillance program for fetuses identified as SGA results in a lower risk of adverse fetal outcome, compared with cases of SGA fetuses not identified antepartum. Copyright (c) 2005 ISUOG. Published by John Wiley & Sons, Ltd.

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