期刊
MEDICAL MYCOLOGY
卷 43, 期 2, 页码 97-115出版社
OXFORD UNIV PRESS
DOI: 10.1080/13693780500035979
关键词
Candida albicans; immunoprevention; prophylaxis; vaccine
资金
- NIAID NIH HHS [R01 AI 24912] Funding Source: Medline
The development of a useful Candida vaccine is a distinct possibility despite the fact that individuals with a lifetime of commensal sensitization do not develop sterile immunity to the organism. An effective Candida vaccine would be invaluable in preventing hematogenously disseminated candidiasis, as well as mucocutaneous disease. This review is a discussion of our current understanding of the interplay between commensal and pathogenic forms of Candida albicans and approaches toward active and passive immunoprevention against candidiasis.
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