期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 15, 期 5, 页码 1371-1373出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2005.01.011
关键词
bicyclic; beta-lactam; antimalarial; Plasmodium falciparum
A series of bicyclic N-substituted and unsubstituted beta-lactams were synthesized and evaluated as targeted potential antimalarials. The compounds MNR4 and MNR5 were found to have highest potency against Plasmodium falciparum in vitro. (c) 2005 Elsevier Ltd. All rights reserved.
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