期刊
BRIEFINGS IN BIOINFORMATICS
卷 6, 期 1, 页码 6-22出版社
OXFORD UNIV PRESS
DOI: 10.1093/bib/6.1.6
关键词
sequence alignment; local alignment; multiple alignment; synteny detection; rearrangements; hidden Morkov model
Starting with the sequencing of the mouse genome in 2002, we have entered a period where the main focus of genomics will be to compare multiple genomes in order to learn about human biology and evolution at the DNA level. Alignment methods are the main computational component of this endeavour. This short review aims to summarise the current status of research in alignments, emphasising large-scale genomic comparisons and suggesting possible directions that will be explored in the near future.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据