期刊
CURRENT ALLERGY AND ASTHMA REPORTS
卷 5, 期 2, 页码 136-141出版社
CURRENT MEDICINE GROUP
DOI: 10.1007/s11882-005-0087-8
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Several subtypes of regulatory or suppressive T cells have been described that can prevent activation of effector T cells in vitro and in vivo in animal models. Recent evidence suggests a deficit in suppressive activity of both CD4(+)CD25(+) regulatory T cells, and interleukin (IL)-10 producing regulatory T cells may play a role in development of allergic sensitization. If therapies can be devised to redress the balance between regulatory and effector T cells, there may be hope for the control and prevention of asthma.
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