期刊
NEUROREHABILITATION AND NEURAL REPAIR
卷 19, 期 1, 页码 33-45出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1545968305274517
关键词
SCI; exercise; electrical stimulation; constraint-induced therapy; rehabilitation; hand function
Objective. To determine the effect of massed practice (MP) versus massed practice combined with somatosensmy stimulation (MP+SS) on cortical plasticity and function in per sons with incomplete tetraplegia. Methods. Ten subjects were assigned to either MP or MP+SS. Mediam nerve stimulation (500 ms train, 10 Hz, I ms pulse duration) was delivered at the intensity eliciting a motor threshold response, Training sessions were 5 d/week for 3 weeks at 2 h/session. Outcome measures included 1) motor evoked potentials (MEPs) elicited via transcranial magnetic stimulation (TMS), motor threshold (MT) and MEP amplitude at 1.2x MT; 2) maximal pinch grip force; 3) Wolf Motor Function Test (WMFT) and jebsen Hand Function Test. Results. The MP+SS group demonstrated significant improvements (P < 0.05) in pinch grip strength (190%), WMFT scores (52%), andjebsen test scores (33%), whereas the MP group demonstrated significant improvement (P < 0.05) only in Jebsen test scores (11%). No significant changes were detected in cortical excitability in the MP+SS or MP group. Conclusions. The findings of this preliminary study suggest that MP+SS results in greater increases in pinch strength and timed Junctional test scores than ME Optimal stimulation paradigms and training methods are needed to further test this strategy.
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