4.7 Review

Protein expression in Pichia pastoris: recent achievements and perspectives for heterologous protein production

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Impact of Gene Dosage on the Production of Lipase from Rhizopus chinensis CCTCC M201021 in Pichia pastoris

Chong Sha et al.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2013)

Article Biotechnology & Applied Microbiology

A novel cholesterol-producing Pichia pastoris strain is an ideal host for functional expression of human Na,K-ATPase α3β1 isoform

Melanie Hirz et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2013)

Article Biotechnology & Applied Microbiology

High-level expression and characterization of a chimeric lipase from Rhizopus oryzae for biodiesel production

Xiao-Wei Yu et al.

BIOTECHNOLOGY FOR BIOFUELS (2013)

Article Biotechnology & Applied Microbiology

Endogenous signal peptides efficiently mediate the secretion of recombinant proteins in Pichia pastoris

Shuli Liang et al.

BIOTECHNOLOGY LETTERS (2013)

Article Biotechnology & Applied Microbiology

Identification and characterization of PGCW14: a novel, strong constitutive promoter of Pichia pastoris

Shuli Liang et al.

BIOTECHNOLOGY LETTERS (2013)

Article Biotechnology & Applied Microbiology

Improved secretion of Candida antarctica lipase B with its native signal peptide in Pichia pastoris

Ashok Kumar Prasanna Vadhana et al.

ENZYME AND MICROBIAL TECHNOLOGY (2013)

Review Microbiology

Pichia pastoris: protein production host and model organism for biomedical research

Brigitte Gasser et al.

FUTURE MICROBIOLOGY (2013)

Article Biochemistry & Molecular Biology

Production of sialylated O-linked glycans in Pichia pastoris

Stephen R. Hamilton et al.

GLYCOBIOLOGY (2013)

Article Biotechnology & Applied Microbiology

Disruption of YPS1 and PEP4 genes reduces proteolytic degradation of secreted HSA/PTH in Pichia pastoris GS115

Min Wu et al.

JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2013)

Article Biotechnology & Applied Microbiology

Repressible promoters - A novel tool to generate conditional mutants in Pichia pastoris

Marizela Delic et al.

MICROBIAL CELL FACTORIES (2013)

Article Biotechnology & Applied Microbiology

Induction without methanol: novel regulated promoters enable high-level expression in Pichia pastoris

Roland Prielhofer et al.

MICROBIAL CELL FACTORIES (2013)

Review Biotechnology & Applied Microbiology

Can too many copies spoil the broth?

Rochelle Aw et al.

MICROBIAL CELL FACTORIES (2013)

Article Multidisciplinary Sciences

Characterization of the Pichia pastoris Protein-O-mannosyltransferase Gene Family

Juergen H. Nett et al.

PLOS ONE (2013)

Review Biochemistry & Molecular Biology

Yeast metabolic engineering - Targeting sterol metabolism and terpenoid formation

Tamara Wriessnegger et al.

PROGRESS IN LIPID RESEARCH (2013)

Article Biotechnology & Applied Microbiology

Construction of new Pichia pastoris X-33 strains for production of lycopene and β-carotene

J. M. Araya-Garay et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2012)

Review Biotechnology & Applied Microbiology

Protein secretion in Pichia pastoris and advances in protein production

Leonardo M. Damasceno et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2012)

Article Biotechnology & Applied Microbiology

Optimization of the production of gurmarin, a sweet-taste-suppressing protein, secreted by the methylotrophic yeast Pichia pastoris

Maud Sigoillot et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2012)

Article Biochemical Research Methods

Sensitive high-throughput screening for the detection of reducing sugars

Andrea Mellitzer et al.

BIOTECHNOLOGY JOURNAL (2012)

Article Biochemistry & Molecular Biology

Gss1 protein of the methylotrophic yeast Pichia pastoris is involved in glucose sensing, pexophagy and catabolite repression

Andriy S. Polupanov et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)

Article Multidisciplinary Sciences

Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K+ Ion Channel

Stephen G. Brohawn et al.

SCIENCE (2012)

Article Chemistry, Organic

A novel multi-enzymatic high throughput assay for transaminase activity

Katrin Weinhandl et al.

TETRAHEDRON (2012)

Article Biotechnology & Applied Microbiology

GAP Promoter Library for Fine-Tuning of Gene Expression in Pichia pastoris

Xiulin Qin et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2011)

Article Biotechnology & Applied Microbiology

Hydrophobin signal sequence mediates efficient secretion of recombinant proteins in Pichia pastoris

Kirsten Kottmeier et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2011)

Article Biochemistry & Molecular Biology

Lipid-binding surfaces of membrane proteins: Evidence from evolutionary and structural analysis

Larisa Adamian et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)

Article Biotechnology & Applied Microbiology

High-quality genome sequence of Pichia pastoris CBS7435

Andreas Kueberl et al.

JOURNAL OF BIOTECHNOLOGY (2011)

News Item Pharmacology & Pharmacy

FDA approves kallikrein inhibitor to treat hereditary angioedema

Cheryl A. Thompson

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2010)

Review Biotechnology & Applied Microbiology

Engineering of protein secretion in yeast: strategies and impact on protein production

Alimjan Idiris et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)

Review Biotechnology & Applied Microbiology

Engineering of glycosylation in yeast and other fungi: current state and perspectives

Karen De Pourcq et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)

Article Biotechnology & Applied Microbiology

Identification and characterisation of novel Pichia pastoris promoters for heterologous protein production

Gerhard Stadlmayr et al.

JOURNAL OF BIOTECHNOLOGY (2010)

Article Biochemistry & Molecular Biology

Residue-specific global fluorination of Candida antarctica lipase B in Pichia pastoris

Nediljko Budisa et al.

MOLECULAR BIOSYSTEMS (2010)

Article Biotechnology & Applied Microbiology

Biopharmaceutical benchmarks 2010

Gary Walsh

NATURE BIOTECHNOLOGY (2010)

Article Biotechnology & Applied Microbiology

Stepwise engineering of a Pichia pastoris D-amino acid oxidase whole cell catalyst

Sandra Abad et al.

MICROBIAL CELL FACTORIES (2010)

Article Biochemical Research Methods

Secretion and proteolysis of heterologous proteins fused to the Escherichia coli maltose binding protein in Pichia pastoris

Zhiguo Li et al.

PROTEIN EXPRESSION AND PURIFICATION (2010)

Article Biotechnology & Applied Microbiology

Phosphate-Responsive Promoter of a Pichia pastoris Sodium Phosphate Symporter

Jungoh Ahn et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2009)

Article Biochemistry & Molecular Biology

Identification of key DNA elements involved in promoter recognition by Mxr1p, a master regulator of methanol utilization pathway in Pichia pastoris

Balla Venkata Kranthi et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2009)

Article Biochemistry & Molecular Biology

Lipid analysis of mitochondrial membranes from the yeast Pichia pastoris

T. Wriessnegger et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2009)

Review Pharmacology & Pharmacy

Computational analysis of membrane proteins: the largest class of drug targets

Yalini Arinaminpathy et al.

DRUG DISCOVERY TODAY (2009)

Article Biotechnology & Applied Microbiology

Directed gene copy number amplification in Pichia pastoris by vector integration into the ribosomal DNA locus

Hans Marx et al.

FEMS YEAST RESEARCH (2009)

Article Biotechnology & Applied Microbiology

An upstream activation sequence controls the expression of AOX1 gene in Pichia pastoris

Yaoji Xuan et al.

FEMS YEAST RESEARCH (2009)

Article Biotechnology & Applied Microbiology

Degradation of HSA-AX15(RUK) when expressed in Pichia pastoris can be reduced via the disruption of YPS1 gene in this yeast

Xue Qin Yao et al.

JOURNAL OF BIOTECHNOLOGY (2009)

Article Biotechnology & Applied Microbiology

Biotechnological strains of Komagataella (Pichia) pastoris are Komagataella phaffii as determined from multigene sequence analysis

Cletus Paul Kurtzman

JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2009)

Article Biotechnology & Applied Microbiology

Genome sequence of the recombinant protein production host Pichia pastoris

Kristof De Schutter et al.

NATURE BIOTECHNOLOGY (2009)

Article Biochemical Research Methods

Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology

Pieter P. Jacobs et al.

NATURE PROTOCOLS (2009)

Article Biotechnology & Applied Microbiology

Open access to sequence: Browsing the Pichia pastoris genome

Diethard Mattanovich et al.

MICROBIAL CELL FACTORIES (2009)

Article Biotechnology & Applied Microbiology

Genome, secretome and glucose transport highlight unique features of the protein production host Pichia pastoris

Diethard Mattanovich et al.

MICROBIAL CELL FACTORIES (2009)

Article Multidisciplinary Sciences

Crystal structure of human aquaporin 4 at 1.8 Å and its mechanism of conductance

Joseph D. Ho et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biotechnology & Applied Microbiology

Increasing the cell viability and heterologous protein expression of Pichia pastoris mutant deficient in PMR1 gene by culture condition optimization

Hong Liang Zhao et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2008)

Article Biochemistry & Molecular Biology

Promoter library designed for fine-tuned gene expression in Pichia pastoris

Franz S. Hartner et al.

NUCLEIC ACIDS RESEARCH (2008)

Article Biochemistry & Molecular Biology

Decrease of hirudin degradation by deleting the KEXI gene in recombinant Pichia pastoris

Zhenhua Ni et al.

Article Biochemical Research Methods

High-level expression and purification of recombinant human catalase in Pichia pastoris

Xun-Long Shi et al.

PROTEIN EXPRESSION AND PURIFICATION (2007)

Article Biotechnology & Applied Microbiology

Translation elongation factor 1-α gene from Pichia pastoris:: molecular cloning, sequence, and use of its promoter

Jungoh Ahn et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2007)

Article Biochemistry & Molecular Biology

Lipid composition of peroxisomes from the yeast Pichia pastoris grown on different carbon sources

Tamara Wriessnegger et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2007)

Article Multidisciplinary Sciences

Humanization of yeast to produce complex terminally sialylated glycoproteins

Stephen R. Hamilton et al.

SCIENCE (2006)

Article Biochemistry & Molecular Biology

Mxr1p, a key regulator of the methanol utilization pathway and peroxisomal genes in Pichia pastoris

GP Lin-Cereghino et al.

MOLECULAR AND CELLULAR BIOLOGY (2006)

Article Biochemical Research Methods

Expression and characterization of a housefly cecropin gene in the methylotrophic yeast, Pichia pastoris

Fengliang Jin et al.

PROTEIN EXPRESSION AND PURIFICATION (2006)

Article Biotechnology & Applied Microbiology

Cloning and characterization of the Pichia pastoris MET2 gene as a selectable marker

D Thor et al.

FEMS YEAST RESEARCH (2005)

Article Biotechnology & Applied Microbiology

Reduced proteolysis of secreted gelatin and Yps1-mediated α-factor leader processing in a Pichia pastoris kex2 disruptant

MWT Werten et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2005)

Article Biochemistry & Molecular Biology

Purification of Na+,K+-ATPase expressed in Pichia pastoris reveals an essential role of phospholipid-protein interactions

E Cohen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Biochemistry & Molecular Biology

Heterologous protein production using the Pichia pastoris expression system

S Macauley-Patrick et al.

Review Biochemistry & Molecular Biology

Expression of heterologous proteins in Pichia pastoris:: a useful experimental tool in protein engineering and production

R Daly et al.

JOURNAL OF MOLECULAR RECOGNITION (2005)

Article Biotechnology & Applied Microbiology

Reliable high-throughput screening with Pichia pastoris by limiting yeast cell death phenomena

R Weis et al.

FEMS YEAST RESEARCH (2004)

Review Biotechnology & Applied Microbiology

Advances in the production of human therapeutic proteins in yeasts and filamentous fungi

TU Gerngross

NATURE BIOTECHNOLOGY (2004)

Article Biochemistry & Molecular Biology

The ICL1 gene of Pichia pastoris, transcriptional regulation and use of its promoter

J Menendez et al.

Article Multidisciplinary Sciences

Production of complex human glycoproteins in yeast

SR Hamilton et al.

SCIENCE (2003)

Article Multidisciplinary Sciences

Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichia pastoris

BK Choi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemical Research Methods

Soluble expression and purification of porcine pepsinogen from Pichia pastoris

MA Yoshimasu et al.

PROTEIN EXPRESSION AND PURIFICATION (2002)

Article Biotechnology & Applied Microbiology

Overproduction of BiP negatively affects the secretion of Aspergillus niger glucose oxidase by the yeast Hansenula polymorpha

M van der Heide et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2002)

Article Biochemistry & Molecular Biology

Stable linker peptides for a cellulose-binding domain-lipase fusion protein expressed in Pichia pastoris

M Gustavsson et al.

PROTEIN ENGINEERING (2001)

Article Biochemical Research Methods

Effect of copy number on the expression levels of hepatitis B surface antigen in the methylotrophic yeast Pichia pastoris

A Vassileva et al.

PROTEIN EXPRESSION AND PURIFICATION (2001)

Article Biotechnology & Applied Microbiology

Proteolytic stability of recombinant human serum albumin secreted in the yeast Saccharomyces cerevisiae

HA Kang et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2000)

Review Microbiology

Heterologous protein expression in the methylotrophic yeast Pichia pastoris

JL Cereghino et al.

FEMS MICROBIOLOGY REVIEWS (2000)