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Many P-element insertions affect wing shape in Drosophila melanogaster

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GENETICS
卷 169, 期 3, 页码 1461-1475

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GENETICS SOCIETY AMERICA
DOI: 10.1534/genetics.104.027748

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  1. NIGMS NIH HHS [R15GM65116-01] Funding Source: Medline

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A screen of random, autosomal, homozygous-viable P-element insertions in D. melawogastor found small effects on wing shape in 11 of 50 lines. The effects were due to sing le insertions and remained stable and significant for over 5 years, in repeated, high-resolution measurements. All 11 insertions were within or near protein-coding transcription units, none of which were previously known to affect wing shape. Many sites in the genome can affect wing shape.

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