期刊
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
卷 89, 期 3, 页码 457-473出版社
SPRINGER
DOI: 10.1007/s00253-010-2923-6
关键词
Endophytic actinobacteria; Biodiversity; Natural products; Biotechnology
资金
- National Basic Research Program of China [2010CB833800]
- National Natural Science Foundation of China [30872028, 31000005]
- Natural Science Foundation of the Jiangsu Higher Education Institutions of China [08KJA350001]
- Program of the Demonstration and Study of Standardization Seeding Technology of Jatropha [2007BAD50B0204]
- Natural Science Foundation by Xuzhou Normal University [09XLR12, 09XLR19]
Endophytic actinobacteria, which exist in the inner tissues of living plants, have attracted increasing attention among taxonomists, ecologists, agronomists, chemists and evolutionary biologists. Numerous studies have indicated that these prolific actinobacteria appear to have a capacity to produce an impressive array of secondary metabolites exhibiting a wide variety of biological activity, such as antibiotics, antitumor and anti-infection agents, plant growth promoters and enzymes, and may contribute to their host plants by promoting growth and enhancing their ability of withstanding the environmental stresses. These microorganisms may represent an underexplored reservoir of novel species of potential interest in the discovery of novel lead compounds and for exploitation in pharmaceutical, agriculture and industry. This review focuses on new findings in the isolation methods, bio- and chemical diversity of endophytic actinobacteria and reveals the potential biotechnological application. The facing problems and strategies for biodiversity research and bioactive natural products producing are also discussed.
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