期刊
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
卷 87, 期 6, 页码 2227-2235出版社
SPRINGER
DOI: 10.1007/s00253-010-2681-5
关键词
Bacillus licheniformis; Glucose starvation; Overflow metabolism; Acetoin
资金
- Ministry of Education and Training of Vietnam (MOET)
- Institute of Marine Biotechnology (IMaB)
- German Federal Ministry of Education and Research (BMBF) [0313751B]
The acoABCL and acuABC operons of Bacillus licheniformis DSM13 are strongly induced at the transcriptional level during glucose starvation conditions. Primer extension analyses of this study indicate that the acoABCL operon is controlled by a sigmaL-dependent promoter and the acuABC operon by a sigmaA-dependent promoter. Transcription at the acoA promoter is repressed by glucose but induced by acetoin as soon as the preferred carbon source glucose is exhausted. The acuA promoter shows a similar induction pattern, but its activity is independent from the presence of acetoin. It is demonstrated that the acoABCL operon is mainly responsible for acetoin and 2,3-butanediol degradation in B. licheniformis.
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