期刊
JOURNAL OF ETHNOPHARMACOLOGY
卷 97, 期 3, 页码 453-456出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.jep.2004.11.009
关键词
hyperlipidaemia; pancreatic lipase; anti-lipase activity; medicinal plants
In order to find new pancreatic lipase (triacylglycerol lipase, EC 3.1.1.3) inhibitors from natural sources, 75 medicinal plants belonging to different families were screened for their anti-lipase activity, using a radioactive method. On evaluating the results, methanolic extracts of three plants namely, Eriochloa villosa (Thunb.) Kunth, Orixa japonica Thunb. and Setaria italica (L.) Palib., exhibited strong in vitro anti-lipase activity (above 80%). These plants will be studied further to elucidate the structure and chemical properties of the active compound responsible for anti-lipase action. (c) 2004 Elsevier Ireland Ltd. All rights reserved.
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