期刊
TETRAHEDRON LETTERS
卷 46, 期 12, 页码 2105-2108出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2005.01.149
关键词
beta-acetamido ketones; benzaldehydes; acetophenones; one-pot synthesis; silica sulfuric acid; catalyst; Dakin-West reaction
A one-pot, four-component condensation of an aryl aldehyde, an aryl ketone, acetyl chloride and acetonitrile in the presence of silica sulfuric acid as an active, inexpensive, recoverable and recyclable catalyst is disclosed for the synthesis of beta-acetamido ketones. (C) 2005 Elsevier Ltd. All rights reserved.
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