期刊
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
卷 102, 期 12, 页码 4403-4408出版社
NATL ACAD SCIENCES
DOI: 10.1073/pnas.0409891102
关键词
coelomata; ecdyosozoa; intron evolution; phylogenetics
The relationship between three biologically important groups, arthropods, nematodes, and deuterostomes, remains unresolved. it is unknown whether arthropods are more closely related to nematodes (consistent with the ecdysozoa hypothesis) or to deuterostomes (consistent with coelomata). We present a method in which we use the pattern of spliceosomal intron conservation to develop a series of inequalities that characterize each possible relationship. We find that only the ecdysozoa grouping satisfies these predictions, with P < 10(-6). Simulations show that our method, unlike some previous methods, is largely insensitive to rate variation between branches.
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