4.4 Article

A mild and efficient one-pot synthesis of 2-dihydroimidazoles from aldehydes

期刊

TETRAHEDRON LETTERS
卷 46, 期 13, 页码 2197-2199

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2005.02.025

关键词

dihydroimidazole; aldehyde; 1,2-diamine; N,N-Acetal; N-halosuccinimide; mild reaction

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The reactions of various aldehydes and 1,2-diamines followed by NXS treatment proceed at 0 degrees C to give the corresponding dihydroimidazoles in high yields. The reaction is mild, and many functional groups such as halogens, nitrites, and esters can exist. (c) 2005 Elsevier Ltd. All rights reserved.

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