期刊
NEUROCHEMICAL RESEARCH
卷 30, 期 4, 页码 425-428出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s11064-005-2676-2
关键词
epilepsy; serotonin; blood platelets; SERT; paroxetine binding
Serotonin transporter (SERT) was studied by [H-3]-paroxetine binding in blood platelets from controls and epileptic patients with generalized convulsive seizures. The average K-D and B-Max were not different in the two cases. However, a significant decrease was found in the serotonin transporter density in the platelet membranes from patients having undergone an epileptic seizure less than 4 days before. This circumstance may indicate a homeostatic reaction to the epileptic attack.
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