期刊
NATURE STRUCTURAL & MOLECULAR BIOLOGY
卷 12, 期 4, 页码 378-379出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb908
关键词
-
资金
- NIAMS NIH HHS [AR35186] Funding Source: Medline
Molecular motors play a central role in cytoskeletal-mediated cellular processes and thus present an excellent target for cellular control by pharmacological agents. Yet very few such compounds have been found. We report here the structure of blebbistatin, which inhibits specific myosin isoforms, bound to the motor domain of Dictyostelium discoideum myosin II. This reveals the structural basis for its specificity and provides insight into the development of new agents.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据