期刊
FEMS MICROBIOLOGY REVIEWS
卷 29, 期 2, 页码 377-390出版社
OXFORD UNIV PRESS
DOI: 10.1016/j.femsre.2005.01.003
关键词
Campylobacter jejuni; glycome; lipooligosaccharide; capsule; glycosylated flagellin; N-linked glycosylation system
类别
Microbial cell surface glycans in the form of glycolipids and glycoproteins frequently play important roles in cell-cell interaction and host immune responses. Given the likely importance of these surface structures in the survival and pathogenesis of Campylobacter jejuni, a concerted effort has been made to characterise these determinants genetically and structurally since the genome was sequenced in 2000. We review the considerable progress made in characterising the Campylobacter glycome including the lipooligosaccharide (LOS), the capsule and O- and N-linked protein glycosylation systems, and speculate on the, roles played by glycan surface structures in the life-cycle of C jejuni. (c) 2005 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
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