期刊
JOURNAL OF NATURAL PRODUCTS
卷 68, 期 4, 页码 620-622出版社
AMER CHEMICAL SOC
DOI: 10.1021/np040199j
关键词
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Three new bromophenols, 2,2',3,6,6'-pentabromo-3',4,4',5-tetrahydroxydibenzyl ether (1), bis(2,3,6-tribromo-4,5-dihydroxyphenyl)methane (2), and 2,2',3,5',6-pentabromo-3',4,4',5-tetrahydroxydiphenylmethane (3), were isolated from the red alga Symphyocladia latiuscula. Two bromophenols, 2,3,6-tribromo-4,5-dihydroxymethylbenzene (4) and 2,3,6-tribromo-4,5-dihydroxybenzaldehyde (5), were also reported for the first time as natural products. Their structures were elucidated on the basis of chemical and spectroscopic methods including HREIMS, HRFABMS, and 1D and 2D NMR spectral techniques. Compounds 1-5 exhibited significant aldose reductase inhibitory activity.
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