期刊
NEUROREPORT
卷 16, 期 5, 页码 457-461出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00001756-200504040-00008
关键词
auditory oddball; automatic attention; deviance detection; prefrontal cortex; superior temporal cortex
资金
- NIMH NIH HHS [MH58251, K23 MH073091-02, K23 MH073091-03, K23 MH073091-01A1, K23 MH073091, K23 MH073091-04] Funding Source: Medline
- NINDS NIH HHS [NS41328] Funding Source: Medline
Activity within fronto-striato-temporal regions during processing of unattended auditory deviant tones and an auditory target detection task was investigated using event-related functional magnetic resonance imaging. Activation within the middle frontal gyrus, inferior frontal gyrus, anterior cingulate gyrus, superior temporal gyrus, thalamus, and basal ganglia were analyzed for differences in activity patterns between the two stimulus conditions. Unattended deviant tones elicited robust activation in the superior temporal gyrus; by contrast, attended tones evoked stronger superior temporal gyrus activation and greater frontal and striatal activation. The results suggest that attention enhances neural activation evoked by auditory pitch deviance in auditory brain regions, possibly through top-down control from the dorsolateral prefrontal cortex involved in goal-directed selection and response generation. (c) 2005 Lippincott Williams A Wilkins.
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