期刊
BRITISH JOURNAL OF CANCER
卷 92, 期 7, 页码 1182-1187出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bjc.6602476
关键词
-
类别
资金
- FIC NIH HHS [D43 TW000671, D43-TW00671] Funding Source: Medline
- NCI NIH HHS [P01-CA83638, R01 CA098951, P50 CA083638] Funding Source: Medline
- NICHD NIH HHS [K12 HD043459, K12-HD43549] Funding Source: Medline
In this review, we discuss the recent identification in vivo of a population of CD11c(+) cells exhibiting simultaneous expression of both endothelial and dendritic cell markers, termed vascular leukocytes (VLCs). VLCs are highly represented in human ovarian carcinomas and, depending on the milieu, can assemble into functional blood vessels or act as antigen-presenting cells. The identification of dendritic cell precursors as bipotent cells has important implications for the physiopathology and therapy of tumours. VLCs emerge as a novel therapeutic target against tumour vascularisation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据