期刊
ORGANIC LETTERS
卷 7, 期 8, 页码 1577-1580出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol050246e
关键词
-
资金
- NCI NIH HHS [CA27489] Funding Source: Medline
A practical organocatalytic process for the synthesis of optically active, highly substituted (x-hydroxy-ketones was achieved through asymmetric desymmetrization (ADS) of prochiral ketones. The ADS and O-N bond reduction reaction of prochiral ketone with nitrosobenzene in the presence of a catalytic amount of chiral amine or amino acid produced the tandem ADS/O-N bond reduced products as single diastereomers with good yields and excellent enantiomeric excesses.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据