期刊
ORGANIC LETTERS
卷 7, 期 8, 页码 1517-1520出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol0501727
关键词
-
资金
- NIGMS NIH HHS [GM56414, 5 T32 GM08349] Funding Source: Medline
[GRAPHICS] We have evaluated the effects of microwave irradiation on the solid-phase synthesis of beta-peptides. Sequences designed to adopt the 14-helix, especially those containing the structure-promoting residue trans-2-aminocyclohexanecarboxylic acid (ACHC), suffer from poor synthetic efficiency under standard SPPS conditions. A comparison of microwave and conventional heating shows that both provide excellent synthetic results for shorter sequences; however, we identify a clear benefit from microwave irradiation for longer beta-peptides.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据