期刊
BIOINFORMATICS
卷 21, 期 8, 页码 1308-1310出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bti227
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- NIGMS NIH HHS [GM67165] Funding Source: Medline
Along with their mutating sequences, protein structures change in time. Analyzing a formate dehydrogenase domain that is evolutionarily related to ferredoxin, but simultaneously contains all the structural elements of a beta-Grasp fold, we illustrate here a mechanism termed as structural drift, by which changes to a protein fold can occur.
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