期刊
BEHAVIOURAL BRAIN RESEARCH
卷 159, 期 1, 页码 55-61出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbr.2004.10.002
关键词
anxiety; avoidance; illumination; Lux; elevated plus maze; rat
The effect of the gradient of luminosity between the open and the enclosed arms (O/E-Delta Lux) of the elevated plus maze (EPM), upon the level of fear/anxiety in rats submitted to the trial 1/trial 2 paradigm was investigated. Male Wistar rats were assigned to freely explore either of three EPM configuration. with the enclosed arm walls constructed with either translucent glass (O/E-Delta Lux = 11), opaque glass (O/E-Delta Lux = 96) or wood (O/E-Delta Lux = 141), for 2 consecutive days (trial 1/trial 2). Independently of the EPM configuration, rats exhibited increased fear during trial 2 relative to trial 1, thus indicating that the level of O/E-Delta Lux at least in the range used here, is not a determinant variable for the establishment of increased anxiety induced by prior maze experience. The groups tested under 11 and 141 O/E-Delta Lux were those who exhibited the low and higher level of open arm avoidance, respectively. There was also an increased open arms avoidance over trial 1 in rats tested under 11 and 96 O/E-Delta Lux only. These results su gest that the enclosed arm preference of rats during trial 1 EPM procedure may be changed by the level of gg O/E-Delta Lux of the test. The present results are discussed with respect to the controversy regarding the role of luminosity on EPM performance. (c) 2004 Elsevier B.V. All rights reserved.
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