期刊
FEBS LETTERS
卷 579, 期 11, 页码 2307-2312出版社
WILEY
DOI: 10.1016/j.febslet.2005.03.025
关键词
chloroplast; Cu/Zn superoxide dismutase; metallo chaperone; copper
In plant chloroplasts two superoxide dismutase (SOD) activities occur, FeSOD and Cu/ZnSOD, with reciprocal regulation in response to copper availability. This system presents a unique model to study the regulation of metal-cofactor delivery to an organelle. The Arabidopsis thaliana gene AtCCS encodes a functional homolog to yeast Ccs1p/Lys7p, a copper chaperone for SOD. The AtCCS protein was localized to chloroplasts where it may supply copper to the stromal Cu/ZnSOD. AtCCS mRNA expression levels are upregulated in response to Cu-feeding and senescence. We propose that AtCCS expression is regulated to allow the most optimal use of Cu for photosynthesis. (c) 2005 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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