期刊
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
卷 293, 期 1, 页码 455-463出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jmmm.2005.02.040
关键词
magnetic targeting; drug delivery; shear-induced diffusion; network model; magnetic field design; simulation
A mathematical model for targeted drug delivery using magnetic particles is developed. This includes a diffusive flux of particles arising from interactions between erythrocytes in the microcirculation. The model is used to track particles in a vessel network. Magnetic field design is discussed and we show that it is impossible to specifically target internal regions using an externally applied field. (c) 2005 Elsevier B.V. All rights reserved.
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