期刊
BIOPHYSICAL JOURNAL
卷 88, 期 5, 页码 3118-3132出版社
CELL PRESS
DOI: 10.1529/biophysj.104.056127
关键词
-
类别
The stationary states of systems with many molecular motors are studied theoretically for uniaxial and centered (asterlike) arrangements of cytoskeletal. laments using Monte Carlo simulations and a two-state model. Mutual exclusion of motors from binding sites of the. laments is taken into account. For small overall motor concentration, the density profiles are exponential and algebraic in uniaxial and centered. lament systems, respectively. For uniaxial systems, exclusion leads to the coexistence of regions of high and low densities of bound motors corresponding to motor traffic jams, which grow upon increasing the overall motor concentration. These jams are insensitive to the motor behavior at the end of the. lament. In centered systems, traffic jams remain small and an increase in the motor concentration leads to a flattening of the pro. le if the motors move inwards, and to the buildup of a concentration maximum in the center of the aster if motors move outwards. In addition to motor density patterns, we also determine the corresponding patterns of the motor current.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据