Modelling magnetic carrier particle targeting in the tumor microvasculature for cancer treatment

Magnetic drug targeting of tumors situated in the cavity of the human body is difficult because the magnetic gradients decrease rapidly with the distance from the magnets. Here computer simulations are used to investigate different techniques to focus small MPs within the microvasculature of tumors. Non-invasive methods were found to have range < 15 cm whilst minimal invasive methods could be applied specifically to small tumors (< 18 mm). (c) 2005 Published by Elsevier B.V.