The leaf oil composition of Zanthoxylum fagara (L.) Sarg. from Monteverde, Costa Rica, and its biological activities

The leaf oil of Zanthoxylumfagara was obtained by hydrodistillation and analyzed by GC/MS. The most abundant oil components were citronellol (26.1%), geraniol (15.3%), citronellal (11.3%), geranial (11.6%) and neral (9.6%). The antimicrobial activity against Bacillus cereus, Pseudontonas aeruginosa, and Aspergillus niger, and the in-vitro cytotoxicity of the oil on MDA-MB-231, Hs 578T, and 5637 human tumor cells were also examined.