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An improved, scalable, and impurity-free process for tolterodine tartrate

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ORGANIC PROCESS RESEARCH & DEVELOPMENT
卷 9, 期 3, 页码 314-318

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AMER CHEMICAL SOC
DOI: 10.1021/op050024w

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Tolterodine tartrate is an anticholinergic muscle relaxant used to treat urinary frequency, urinary urgency, and incontinence in people with unstable bladders. An improved, cost-effective, and impurity-free process for tolterodine tartrate suitable for large-scale commercial production is described here by addressing various scale-up and impurity issues.

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