期刊
TRENDS IN BIOCHEMICAL SCIENCES
卷 30, 期 5, 页码 240-244出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibs.2005.03.008
关键词
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The Mediator complex acts as a bridge, conveying regulatory information from enhancers and other control elements to the basal RNA polymerase II transcription machinery. Mediator is required for the regulated transcription of nearly all RNA polymerase II-dependent genes in Saccharomyces cerevisiae, and post-translational modifications of specific Mediator subunits can affect global patterns of gene transcription.
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