4.7 Article

Thermoregulatory model for prediction of long-term cold exposure

期刊

COMPUTERS IN BIOLOGY AND MEDICINE
卷 35, 期 4, 页码 287-298

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.compbiomed.2004.01.004

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mathematical model; thermoregulation; shivering; cold stress; hypothermia

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A multi-segmental mathematical model has been developed for predicting shivering and thermoregulatory responses during long-term cold exposure. The present model incorporates new knowledge on shivering thermogenesis, including the control and maximal limits of its intensity, inhibition due to a low core temperature, and prediction of endurance time. The model also takes into account individual characteristics of age, height, weight, % body fat, and maximum aerobic capacity. The model was validated against three different cold conditions i.e. water immersion up to 38 h and air exposure. The predictions were found to be in good agreement with the observations. (c) 2004 Published by Elsevier Ltd.

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