4.4 Article

Synthesis of substituted bis(heteroaryl)maleimides

期刊

TETRAHEDRON
卷 61, 期 19, 页码 4585-4593

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2005.03.016

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bis(heteroaryl)maleimides; Suzuki cross-coupling

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Substituted bis(fur-2-yl), bis(fur-3-yl) and bis(thien-2-yl) maleimides with potential antidiabetic properties are described. Their synthesis involves, as a key step, a Suzuki cross-coupling between various boron derivatives and the diiodomaleimides. Therefore, a wide range of substituted symmetric and non-symmetric maleimide derivatives can be prepared. (c) 2005 Elsevier Ltd. All rights reserved.

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