期刊
JOURNAL OF PHYSICAL CHEMISTRY B
卷 109, 期 18, 页码 8570-8573出版社
AMER CHEMICAL SOC
DOI: 10.1021/jp051163i
关键词
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In time- and spatially resolved experiments, singlet molecular oxygen, O-2(a(1)Delta(g)), was created in a single nerve cell upon irradiation of a sensitizer incorporated in the cell nucleus using a focused laser beam. The singlet oxygen thus produced was detected by its infrared phosphorescence. Data obtained indicate that, contrary to common perception, this reactive species can be quite long-lived in a cell and, as such, can diffuse over appreciable distances including across the cell membrane into the extra-cellular environment. These results provide a new perspective for mechanistic studies of photoinduced cell death and intracellular signaling
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