期刊
BIOORGANIC & MEDICINAL CHEMISTRY
卷 13, 期 10, 页码 3513-3518出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2005.02.055
关键词
heterocycles; pteridine; pyrimidine; uracil; anticancer
Several pteridine analogues 4-13, 23-26 have been synthesized and tested in vitro against three cancer cell lines, MCF7 (breast), NCl-H460 (lung) and SF-268 (CNS). All tested pteridines can serve as novel templates for the anticancer chemotherapy and can serve as new leads in cancer chemotherapy. (c) 2005 Elsevier Ltd. All rights reserved.
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