Electrochemical sensor for the determination of parathion based on p-tert-butylcalix[6]arene-1,4-crown-4 sol-gel film and its characterization by electrochemical methods

A novel sensor for the determination of parathion based on p-tert-butylcalix[6]-1,4-crown-4 as functional monomer was fabricated by sol-gel method using molecularly imprinted technology. The electrochemical behavior of parathion at the imprinted p-tert-butylcalix[6]arene-1,4-crown-4 sol-gel film sensor was characterized by cyclic voltammetry, linear sweep voltammetry, chronoamperometry and alternating current impedance spectroscopy. A fast response of parathion can be obtained after being incubated in 0.1 M phosphonate buffer solution contain appropriate amount of parathion for 20 min. A linear response over parathion concentration in the range of 5.0 x 10(-9) to 1.0 x 10(-4) M was exhibited with a detection limit of 1.0 x 10(-9) M (S/N = 3). This imprinted film sensor has been applied in determination of parathion in real sample and the results were consistent well with that obtained by high performance liquid chromatography. (c) 2004 Elsevier B.V. All rights reserved.