Pd2(dba)3/Xantphos-catalyzed cross-coupling of thiols and aryl bromides/triflates

The cross-coupling of aliphatic and aromatic thiols and aryl bromides/triflates mediated by a Pd-2(dba)(3)/Xantphos catalytic system in refluxing xylene (140 degrees C) affords the corresponding aryl thioethers in good to excellent yields. (c) 2005 Elsevier Ltd. All rights reserved.