Synthesis of NOBIN derivatives for asymmetric catalysis

This account highlighted the recent advances of our research on the synthesis of enantiopure 2-amino-2'-hydroxy-1,1'-binaphthyl (NOBIN) and its derivatives as well as their applications in asymmetric catalysis, including diethyl zinc addition to aldehydes, allylic addition to aldehydes, allylic substitutions, and hetero-Diels-Alder reactions.