期刊
SENSORS
卷 5, 期 6-10, 页码 377-393出版社
MDPI
DOI: 10.3390/s5060377
关键词
DNA-electrochemical biosensor; DNA damage; damage to DNA bases; oxidative stress; biomarker of DNA damage; 8-oxo-7,8-dihydroxguanine (8-oxoGua); 8-oxo-7,8-dihydro-2 '-deoxyguanosine (8-oxodGuo)
Electrochemical devices have received particular attention due to their rapid detection and great sensitivity for the evaluation of DNA-hazard compounds interaction mechanisms. Several types of bioanalytical method use nucleic acids probes to detect DNA damage. This article reviews current directions and strategies in the development and applications of electrochemical DNA sensors for the detection of DNA damage.
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