期刊
CORTEX
卷 41, 期 3, 页码 354-363出版社
MASSON DIVISIONE PERIODICI
DOI: 10.1016/S0010-9452(08)70272-7
关键词
diffusion tensor imaging; white matter; reading; dyslexia
资金
- NEI NIH HHS [EY 015000] Funding Source: Medline
We investigated the white matter structure in children (n = 14) with a wide range of reading performance levels using diffusion tensor imaging (DTI), a form of magnetic resonance imaging. White matter structure in a left temporo-parietal region that had been previously described as covarying with reading skill in adult readers also differs between children who are normal and poor readers. Specifically, the white matter structure measured using fractional anisotropy (FA) and coherence index (CI) significantly correlated with behavioral measurements of reading, spelling, and rapid naming performance. In general, lower anisotropy and lower coherence were associated with lower performance scores. Although the magnitude of the differences in children are smaller than those in adults, the results support the hypothesis that the structure of left temporoparietal neural pathways is a significant component of the neural system needed to develop fluent reading.
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