Antioxidants from a Chinese medicinal herb -: Psoralea corylifolia L.

The powder and extracts of Psoralea corylifolia L. were tested in lard at 100 degreesC by using the oxidative stability instrument (OSI) and were found to have strong antioxidant effects. Six compounds, bakuchiol, psoralen, isopsoralen, corylifolin, corylin and psoralidin were isolated from the herb and identified by UV, IR, Mass, H-1 and C-13 NMR spectra and melting point. Their antioxidant activities were investigated individually and compared with butylated hydroxytoluene (BHT) and alpha-tocopherol by the OSI at 100 degreesC. The results showed that bakuchiol, corylifolin, corylin and psoralidin had strong antioxidant activities, and especially psoralidin (stronger antioxidant property than BHT), but psoralen and isopsoralen had no antioxidant activities at 0.02% and 0.04% levels. The antioxidant activities of the compounds decrease in the following order: Psoralidin > BHT > alpha-tocopherol > bakuchiol > corylifolin > corylin > isopsoralen similar to psoralen. (C) 2004 Elsevier Ltd. All rights reserved.