期刊
FASEB JOURNAL
卷 19, 期 8, 页码 875-879出版社
WILEY
DOI: 10.1096/fj.04-3609hyp
关键词
embryogenesis; UTR; genomic module; protein coding genes; microRNA gene cluster
Over the past two decades a variety of mechanisms regulating cellular differentiation have been uncovered. These include signaling by morphogens or membrane-associated ligands and asymmetric segregation of cytoplasmic components. Most of these processes are driven by protein coding genes. Here I describe another possible cellular differentiation mechanism that involves asymmetric segregation of micro RNAs, a group of recently discovered non-protein coding genes that have been shown to be involved in differentiation.-Bentwich, I. A postulated role for microRNA in cellular differentiation.
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