4.2 Article

Roles of Kupffer cells in alcoholic liver disease

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ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
卷 29, 期 6, 页码 1116-1120

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LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.ALC.0000168169.20591.64

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Kupffer cells; reactive oxygen species; tumor necrosis factor-alpha; sex difference; thalidomide; PPAR-gamma agonist; metformin

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This article summarizes presentations at the 2004 International Society for Biomedical Research on Alcoholism held in Heidelberg/Mannheim, Germany. The organizers and chairpersons were Yoshiyuki Takei and Gavin E Arteel. The presentations were on 1) Kupffer cell-derived mediators involved in alcoholic liver disease: reactive oxygen and nitrogen species, by Gavin E. Arteel; 2) Kupffer cell-derived mediators in alcoholic liver disease: tumor necrosis factor-a, by Laura E. Nagy; 3) metformin prevents acute alcohol-induced fat accumulation in mouse liver, by Ina Bergheim; 4) gender difference in alcoholic liver disease, by Nobuyuki Enomoto; and 5) Kupffer cells as a therapeutic target of alcoholic liver disease, by Yoshiyuki Takei.

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